UKTIS is the sole dedicated UK provider of evidence-based information on fetal risk following pharmacological and other potentially toxic pregnancy exposures. Established in London in 1983, and one of the founder members of the European Network of Teratology information Services (ENTIS), UKTIS was subsequently transferred to be part of the Newcastle National Poisons Information Service in 1995. UKTIS aims to support the appropriate use of medicines in pregnancy and to advise on management after in utero exposure to potentially harmful substances. In 2014 UKTIS launched a new public facing website bumps best use of medicines in pregnancy (www.medicinesinpregnancy.org), which offers a library of openly available, patient-focussed information sheets to compliment the scientific reviews that UKTIS produces for health care providers (available on toxbase.org, registration required for NHS users; subscriptions available for non-UK and private access). UKTIS also contributes to global teratogen surveillance by undertaking systematic follow-up of pregnancies reported to the service so that fetal outcomes can be recorded and analysed with data collected by equivalent services around the world.